© 2003 Robert A. Freitas Jr. All Rights Reserved.

Robert A. Freitas Jr., Nanomedicine, Volume IIA: Biocompatibility, Landes Bioscience, Georgetown, TX, 2003

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1938. F.A. Ofosu, J. Fareed, L.M. Smith, N. Anvari, D. Hoppensteadt, M.A. Blajchman, “Inhibition of factor X, factor V and prothrombin activation by the bis(lactobionic acid amide) LW10082,” Eur. J. Biochem. 203(15 January 1992):121-125.

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1943. R.M. Mesters, M.J. Heeb, J.H. Griffin, “Interactions and inhibition of blood coagulation factor Va involving residues 311-325 of activated protein C,” Protein Sci. 2(September 1993):1482-1489.

1944. H. Banninger, T. Hardegger, A. Tobler, A. Barth, P. Schupbach, W. Reinhart, B. Lammle, M. Furlan, “Fibrin glue in surgery: frequent development of inhibitors of bovine thrombin and human factor V,” Br. J. Haematol. 85(November 1993):528-532.

1945. E. Suehisa, M. Toku, N. Akita, R. Fushimi, T. Takano, H. Tada, Y. Iwatani, N. Amino, “Study on an antibody against F1F2 fragment of human factor V in a patient with Hashimoto’s disease and bullous pemphigoid,” Thromb. Res. 77(1 January 1995):63-68.

1946. T. Koyama, T. Saito, T. Kusano, S. Hirosawa, “Factor V inhibitor associated with Sjogren’s syndrome,” Br. J. Hematol. 89(April 1995):893-896.

1947. V.D. Chouhan, R.A. De La Cadena, C. Nagaswami, J.W. Weisel, M. Kajani, A.K. Rao, “Simultaneous occurrence of human antibodies directed against fibrinogen, thrombin, and factor V following exposure to bovine thrombin: effects on blood coagulation, protein C activation and platelet function,” Thromb. Haemost. 77(February 1997):343-349.

1948. S.J. Israels, M.T. Leaker, “Acquired inhibitors to factors V and X after exposure to topical thrombin: interference with monitoring of low molecular weight heparin and warfarin,” J. Pediatr. 131(September 1997):480-483.

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1950. P. Knobl, K. Lechner, “Acquired factor V inhibitors,” Baillieres Clin. Haematol. 11(June 1998):305-318.

1951. C.P. Reutelingsperger, J.M. Kop, G. Hornstra, H.C. Hemker, “Purification and characterization of a novel protein from bovine aorta that inhibits coagulation. Inhibition of the phospholipid-dependent factor-Xa-catalyzed prothrombin activation, through a high-affinity binding of the anticoagulant to the phospholipids,” Eur. J. Biochem. 173(5 April 1988):171-178.

1952. P. Wildgoose, W. Kisiel, “Inhibition of prothrombin activation by factor X and factor IX Gla-peptides,” Biochem. Biophys. Res. Commun. 152(16 May 1988):1207-1212.

1953. W.R. Church, T.L. Messier, M.M. Tucker, K.G. Mann, “An inhibitory monoclonal antibody to factor X that blocks prothrombin activation but not prothrombinase enzyme assembly,” Blood 72(December 1988):1911-1921.

1954. R.D. Leach, S.A. DeWind, C.W. Slattery, E.C. Herrmann, “Choline inhibition of prothrombin activation,” Thromb. Res. 62(15 June 1991):635-648.

1955. S. Tanabe, T. Tamaki, Y. Wada, “Sphingosine inhibits factor Xa-catalyzed prothrombin activation on the surface of cultured calf pulmonary artery endothelium perturbed by hydrogen peroxide,” Thromb. Res. 67(1 July 1992):115-122.

1956. G.H. Goldsmith, S.S. Pierangeli, D.W. Branch, A.E. Gharavi, E.N. Harris, “Inhibition of prothrombin activation by antiphospholipid antibodies and beta 2-glycoprotein 1,” Br. J. Haematol. 87(July 1994):548-554.

1957. S.S. Pierangeli, G.H. Goldsmith, D.W. Branch, E.N. Harris, “Antiphospholipid antibody: functional specificity for inhibition of prothrombin activation by the prothrombinase complex,” Br. J. Haematol. 97(June 1997):768-774.

1958. S.F. Mohammad, M.D. Hardison, H.Y. Chuang, R.G. Mason, “Adhesion of human blood platelets to glass polymer surfaces. II. Demonstration of the presence of a natural platelet adhesion inhibitor in plasma and serum,” Haemostasis 5(1976):96-114; N.C. Sharma, S.F. Mohammad, H.Y. Chuang, R.G. Mason, “Isolation and some of the physicochemical and immunologic properties of a platelet adhesion inhibitor from human serum,” Thromb. Res. 17(1 March 1980):683-695.

1959. R. Munro, C.P. Jones, R.T. Sawyer, “Calin – a platelet adhesion inhibitor from the saliva of the medicinal leech,” Blood Coagul. Fibrinolysis 2(February 1991):179-184.

1960. E.M. Lyle, T. Fujita, M.W. Conner, T.M. Connolly, G.P. Vlasuk, J.L. Lynch Jr., “Effect of inhibitors of factor Xa or platelet adhesion, heparin, and aspirin on platelet deposition in an atherosclerotic rabbit model of angioplasty injury,” J. Pharmacol. Toxicol. Methods 33(February 1995):53-61.

1961. G.H. van Zanten, T.M. Connolly, M.E. Schiphorst, S. de Graaf, P.J. Slootweg, J.J. Sixma, “Recombinant leech antiplatelet protein specifically blocks platelet deposition on collagen surfaces under flow conditions,” Arterioscler. Thromb. Vasc. Biol. 15(September 1995):1424-1431.

1962. N.D. Kon, K.J. Hansen, M.B. Martin, J.W. Meredith, J.H. Meredith, A.R. Cordell, “Inhibition of platelet deposition on polytetrafluoroethylene grafts by antiplatelet agents,” Surgery 96(November 1984):870-873.

1963. R. Konishi, R. Shimizu, L. Firestone, F.R. Walters, W.R. Wagner, W.J. Federspiel, H. Konishi, B.G. Hattler, “Nitric oxide prevents human platelet adhesion to fiber membranes in whole blood,” ASAIO J. 42(1996):850-853.

1964. J.F. Tschopp. E.M. Driscoll, D.X. Mu, S.C. Black, M.D. Pierschbacher, B.R. Lucchesi, “Inhibition of coronary artery reocclusion after thrombolysis with an RGD-containing peptide with no significant effect on bleeding time,” Coron. Artery Dis. 4(September 1993):809-817.

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1966. B.H. Chao, J.A. Jakubowski, B. Savage, E.P. Chow, U.M. Marzec, L.A. Harker, J.M. Maraganore, “Agkistrodon piscivorus platelet aggregation inhibitor: a potent inhibitor of platelet activation,” Proc. Natl. Acad. Sci. (USA) 86(October 1989):8050-8054.

1967. T.M. Connolly, J.W. Jacobs, C. Condra, “An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officinalis leech. I. Identification, isolation, and characterization,” J. Biol. Chem. 267(5 April 1992):6893-6898.

1968. A.I. Schafer, “Antiplatelet therapy,” Am. J. Med. 101(August 1996):199-209.

1969. Etsuko Ito, Ken Suzuki, Masayuki Yamato, Masayuki Yokoyama, Yasuhisa Sakurai, Teruo Okano, “Active platelet movements on hydrophobic/hydrophilic microdomain-structured surfaces,” J. Biomed. Mater. Res. 42(October 1998):148-155.

1970. R.E. Smith, J.F. Martin, “Endogenous mediators and thrombophilia,” Baillieres Clin. Haematol. 7(September 1994):485-497.

1971. H. Patscheke, “Current concepts for a drug-induced inhibition of formation and action of thromboxane A2,” Blut 60(May 1990):261-268.

1972. J.A. Jakubowski, J.M. Maraganore, “Inhibition of coagulation and thrombin-induced platelet activities by a synthetic dodecapeptide modeled on the carboxy-terminus of hirudin,” Blood 75(15 January 1990):399-406.

1973. B.L. Linder, D.S. Goodman, “Studies on the mechanism of the inhibition of platelet aggregation and release induced by high levels of arachidonate,” Blood 60(August 1982):436-445.

1974. S. Joseph, S. Krishnamurthi, V.V. Kakkar, “Effect of the polyamine-spermine on agonist-induced human platelet activation-specific inhibition of `aggregation-independent’ events induced by thrombin, but not by collagen, thromboxane mimetic, phorbol ester or calcium ionophore,” Thromb. Haemost. 57(7 April 1987):191-195.

1975. M.J. Rohrer, A.S. Kestin, P.A. Ellis, M.R. Barnard, L. Rodino, W.L. Breckwoldt, J.M. Li, A.D. Michelson, “High-dose heparin suppresses platelet alpha granule secretion,” J. Vasc. Surg. 15(June 1992):1000-1008, 1008-1009 (discussion).

1976. A. Nguyen, C.H. Gemmell, E.L. Yeo, M.A. Packham, M.L. Rand, “Ethanol inhibits thrombin-induced secretion of the contents of human platelet dense and alpha-granules and lysosomes,” Thromb. Haemost. 80(October 1998):662-667.

1977. C. Watala, M. Boncler, J. Golanski, W. Koziolkiewicz, B. Walkowiak, C.S. Cierniewski, “Release of calcium and P-selectin from intraplatelet granules is hampered by procaine,” Thromb. Res. 94(1 April 1999):1-11.

1978. J. Polgar, G.L. Reed, “A critical role for N-ethylmaleimide-sensitive fusion protein (NSF) in platelet granule secretion,” Blood 94(15 August 1999):1313-1318.

1979. A.S. Gallus, “Aspirin and other platelet-aggregation inhibiting drugs,” Med. J. Aust. 142(7 January 1985):41-47.

1980. G. Leoncini, M. Maresca, C. Colao, E. Buzzi, M. Mazzei, A. Balbi, “Antiplatelet effect of 2-(diethylamino)-7-hydroxychromone,” Pharmacol. Res. 23(February 1991):139-148.

1981. W.H. Frishman, B. Burns, B. Atac, N. Altajar, K. Lerrick, “Novel antiplatelet therapies for treatment of patients with ischemic heart disease: inhibitors of the platelet glycoprotein IIb/IIIa integrin receptor,” Am. Heart. J. 130(October 1995):877-892.

1982. A.I. Schafer, “Antiplatelet therapy with glycoprotein IIb/IIIa receptor inhibitors and other novel agents,” Tex. Heart Inst. 24(1997):90-96.

1983. A.G. Herman, “Rational for the combination of anti-aggregating drugs,” Thromb. Res. 92(15 September 1998):S17-S21.

1984. Y. Matsumoto, K. Marukawa, H. Okumura, T. Adachi, T. Tani, Y. Kimura, “Comparative study of antiplatelet drugs in vitro: distinct effects of cAMP-elevating drugs and GPIIb/IIIa antagonists on thrombin-induced platelet responses,” Thromb. Res. 95(1 July 1999):19-29.

1985. M. Verstraete, “Synthetic inhibitors of platelet glycoprotein IIb/IIIa in clinical development,” Circulation 101(15 February 2000):E76-E80.

1986. K. Schror, “Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis,” Semin. Thromb. Hemost. 23(1997):349-356.

1987. P.A. Gurbel, C.M. O’Connor, C.C. Cummings, V.L. Serebruany, “Clopidogrel: the future choice for preventing platelet activation during coronary stenting?” Pharmacol. Res. 40(August 1999):107-111.

1988. A. Keyser, “Platelet aggregation inhibitors in neurology,” Pharm. World Sci. 15(17 December 1993):243-251.

1989. M.K. Ito, A.R. Smith, M.L. Lee, “Ticlopidine: a new platelet aggregation inhibitor,” Clin. Pharm. 11(July 1992):603-617.

1990. M.C. Chang, H.K. Lin, H.C. Peng, T.F. Huang, “Antithrombotic effect of crotalin, a platelet membrane glycoprotein Ib antagonist from venom of Crotalus atrox,” Blood 91(1 March 1998):1582-1589.

1991. B.B. Weksler, “Prostacyclin,” Prog. Hemost. Thromb. 6(1982):113-138.

1992. S. Elodi, P. Elodi, “Surface-governed molecular regulation of blood coagulation,” Mol. Aspects Med. 6(1983):291-353.

1993. C.T. Esmon, “The regulation of natural anticoagulant pathways,” Science 235(1987):1348-1352; “The roles of protein C and thrombomodulin in the regulation of blood coagulatoin,” J. Biol. Chem. 264(1989):4743-4746.

1994. W.A. Dittman, P.W. Majerus, “Structure and function of thrombomodulin: a natural anticoagulant,” Blood 75(1990):329-336.

1995. G.L. Long, D. Lu, R.L. Xie, M. Kalafatis, “Human protein S cleavage and inactivation by coagulation factor Xa,” J. Biol. Chem. 273(8 May 1998):11521-11526.

1996. Ladislav Chrobak, Petr Dulicek, “Resistance to activated protein C as pathogenic factor of venous thromboembolism,” Acta Medica (Hradec Kralove) 39(1996):55-62; http://www.lfhk.cuni.cz/periodik/actamed/39_2/anchroba.htm

1997. M.J. Heeb, A. Gruber, J.H. Griffin, “Identification of divalent metal ion-dependent inhibition of activated protein C by alpha 2-macroglobulin and alpha 2-antiplasmin in blood and comparisons to inhibition of factor Xa, thrombin, and plasmin,” J. Biol. Chem. 266(15 September 1991):17606-17612.

1998. M. Muldbjerg, S. Markussen, S. Magnusson, T. Halkier, “Bovine factor XIIa inhibitor,” Blood Coagul. Fibrinolysis 4(February 1993):47-54.

1999. M.J. Heeb, R.M. Mesters, G. Tans, J. Rosing, J.H. Griffin, “Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C,” J. Biol. Chem. 268(5 February 1993):2872-2877.

Last updated on 16 April 2004